Topic outline

  • Introduction

    Welcome to this Course!

    With 5 Million people affected in the European Union, celiac disease (CeD) is one of the most common chronic diseases in children and adults. Although reliable serology markers allow easy and inexpensive testing, many patients remain undetected and unnecessarily suffer from symptoms and potential long-term health consequences. One of the reasons for the low diagnostic rate is that CeD may present with a wide variety of symptoms and is, therefore, named as a clinical chameleon.

    If a patient is identified and the guidelines are followed, the diagnosis is usually straightforward. However, it’s important to know about the pitfalls and unreliable tests in order to prevent misdiagnosis.

    The treatment for CeD is a strict and life-long gluten-free diet, which is very effective but also has major impact on the patient’s daily life, eating habits and psychological wellbeing. 

    We invite you to learn more about this common food induced disease in order to identify celiac patients who will benefit from a gluten-free diet.

    Structure, Content and Learning Aims

    The module "Celiac Disease" contains two separate units, which can be worked through in your preferred order.  For each unit, you will have the opportunity to request CME credits upon successful completion of a multiple choice test at the end.

    Please click on the unit headlines to the full overview

    Please click here to see an overview of the whole module

      Unit 1 Background, Clinical Manifestation & Diagnosis of Celiac Disease Unit 2 Therapy and Monitoring of Celiac Disease

    How to Best Follow this Module

    For your own coordination and scheduling: 

    • To go through the entire module that contains two units, you will need about 150 minutes (about 75 minutes for each unit). Downloading further literature or using our integrated links may take additional time. 
    • Every unit consists of a self-assessment test at the beginning, different lessons and a CME test at the end. To make better use of the teaching material and consequently a better learning experience overall, we suggest that the reader first should go through the units only after that they should attempt the CME tests
    • Technical settings

    How to Receive CME For This Module

    To receive your CME certificate, you have to successfully pass the CME multiple-choice test that can be accessed in each of the units of this module.

    European Accreditation:

    This module has been already accredited by the European Accreditation Council for Continuing Medical Education (EACCME) with 2 European CME credits (ECMEC) which is equivalent to a period of 150 minutes of qualification. 

    The EACCME is an institution of the European Union of Medical Specialists (UEMS). Only those e-learning materials that are displayed on the UEMS-EACCME website have formally been accredited. Each medical specialist should claim only those credits that he/she actually spent in the educational activity.

    German Accreditation:

    This module has been accredited by the German Medical Association with XX credits.

    Get started with… 

    Unit 1 -  Background, Clinical Manifestation and Diagnosis

    Unit 2 – Therapy and Follow-up of Celiac Disease

    About Interreg Central Europe Focus IN CD and Danube Transnational Programme CD SKILLS

    Interreg Central Europe is a cohesion policy programme of the European Union (EU) and part of the European Regional Development Fund (ERDF). With a total funding budget of 246 million €, it encourages and supports cooperation beyond borders and between public and private organisations. Interreg CE projects fall into four different thematic priorities, comprising Innovation, Low Carbon, Culture & Environment, and Transport.

    The Danube Transnational Programme (DTP) promotes economic, social and territorial cohesion in the Danube Region through policy integration in selected fields.

    The Danube Transnational Programme finances projects for the development and practical implementation of policy frameworks, tools and services and concrete small-scale pilot investments. Strong complementarities with the broader EU Strategy for the Danube Region (EUSDR) are sought.

    The total programme budget is 274 578 077 euros, including the EU support (231 924 597 €) and the national counterpart (42 653 480 €). Selected projects are financed up to 85% of their costs. The EU support comes from three different funds: European Regional Development Fund (ERDF) (202 095 405,00 €), Instrument for Pre-Accession Assistance II (IPA II) (19 829 192,00 €), European Neighbourhood Instrument (ENI) (10 000 000,00 €).

    The project Focus IN CD - Innovative patient centered health care services - advantages of establishing a close CE network in celiac disease patient health care", No. CE111, belongs to the priority Innovation. With a funding of nearly 1.9 Mio € it aims to substantially improve and harmonize the care of people with celiac disease in Central Europe. Twelve partners from Croatia, Germany, Hungary, Italy and Slovenia are actively involved in this outstanding initiative.

    CD SKILLS project “Improving celiac disease management in the Danube region by raising the awareness, improving the knowledge, and developing better skills” is addressing existing challenges of healthcare sector in celiac disease management in the Danube region.

    Assessment of regional gaps in celiac disease management will be followed by introduction of innovative learning strategy combining traditional lectures and modern e-tools, development of efficient disease detection strategies, and by innovative pilot services. Multisector transnational network will enable knowledge exchange. 

    One of the main aspects of this project is the development of e-tools, particularly e-learning programmes for celiac patients but also for health care professionals in order to increase the knowledge about this chronic food intolerance. Learn more about Focus in CD  and CD SKILLS projects and visit the projects’ websites:  and

      Further information: 

    Technical Settings

    About Focus IN CD

    Conflict of Interest Statement

    Legal Notice and Disclaimer

    Privacy Policy



    Partnership Logos Focus IN CD Project

    • Unit 1 Background, Clinical Manifestation and Diagnosis

      Welcome to Unit 1 Background, Clinical Manifestation & Diagnosis of Celiac Disease

      In Unit 1 you will learn about the prevalence of CeD in the general population and in risk groups. You will understand the impact of the genetic predisposition and potential environmental factors that may be involved in the CeD development. 

      As CeD can present with a huge variety of symptoms which are not restricted to the gastrointestinal tract, it's important to know these symptoms in order to identify patients who should be tested. 

      Of course, you will also explore the different diagnostic approaches and learn which tests are reliable and when you have to be aware of pitfalls that may lead to both false negative or positive diagnosis of CeD. 

      The likely duration that the reader will need to engage with the material is 75 minutes.

      View here the content and learning aims of Unit 1

      Self-Assessment Unit 1

      Lesson 1 - Celiac Disaese Definiton, Prevalence & Pathogenesis

      Lesson 2 The Celiac Iceberg Clinical Presentation and Symptoms

      Lesson 3 Diagnosing Celiac Disease

      • Unit 2 Therapy and Monitoring of Celiac Disease

        Welcome to Unit 2 Therapy & Monitoring of Celiac Disease

        The only available treatment for celiac disease is a strict and lifelong gluten-free diet. On a gluten-free diet, symptoms will improve or even completely resolve in most cases, the antibody levels will gradually normalize and the intestine will usually  recover. 

        Since gluten is contained in a wide variety of commonly eaten foods, the necessary dietary adjustments after a confirmed diagnosis can be challenging. Good knowledge about the gluten-free diet and its implications on daily life are essential to avoid dietary mistakes and involuntary gluten ingestion.

        With the gluten-free diet, all nutrient requirements can be met and dietary supplements are usually not necessary. Although generally healthy, the gluten-free diet requires more careful food choices than a normal diet, especially when certain co-morbidities or lifestyle choices are present as well.

        Besides the medical aspects of celiac disease, including follow-up examinations and co-morbidities, healthcare professionals should be aware of the psychosocial effects celiac disease can have on patients and their families. Good education and peer support/ mentoring from celiac societies/ organizations and/or psychology support are important factors in helping overcome emotional difficulties after diagnosis. 

        The likely duration that the reader will need to engage with the material is 75 minutes.

        View here the content and learning aims of Unit 2

        Self-Assessment Unit 2

        Lesson 1 The Gluten-free Diet What can Patient with Celiac Disease Eat?

        Lesson 2 Health Risks & Benefits of the Gluten-free Diet

        Lesson 3 Psychosocial Consequences

        Lesson 4 Monitoring of Celiac Disease